Thrombolytic Potentials of Some Medicinal Plants Used by the Local People for Cardiovascular Diseases in Bangladesh

Cardiovascular diseases (CVDs) are one of the major causes death in world. Medicinal plants with thrombolytic properties may be used as an alternative to modern medicines for CVDs. The present study was aimed evaluate potential six medicinal available Bangladesh using vitro clot lysis method where streptokinase and ethanol were a positive negative control, respectively. Ethanolic extract at dose 10 mg/ml Arjun tree (Terminalia arjuna), Garlic (Allium sativum), Elephant apple (Dillenia indica), Amla (Phyllanthus emblica), Yellow mombin (Spondias pinnata) Burmese grape (Baccaurea ramiflora) showed 14.18 ± 1.23%, 10.72 0.78%, 8.25 0.42%, 7.08 0.64%, 5.42 0.47% 2.47 0.19% lysis, respectively, whereas standard drug lysed 41.11±0.31% 30,000 IU. From data, it is evident that ethanolic extracts selected possess moderate insignificant activities. Among these plants, exhibited highest activity lowest activity. Through our study, could concluded tree, Garlic, might traditional healing purposes However, further animal studies will prove scientific justification their uses. Conservation efforts should given apple, mombin, grape, save from extinction nature. J. Plant Taxon. 28(2): 405-412, 2021 (December)